Improvement of Interferon-Beta Production in Transient Expression System of CHO DG44 by a Codon Bias Change in Instability Sequence (CRID) of C-terminal of Interferon Beta Gene
Background: Improvement of mRNA stability and therefore, production of interferon beta (IFNb) in Chinese hamster ovary (CHO) cell, as a recombinant protein expression system, is very important. The aim of this study was to investigate this effect by creating a codon bias change in instability sequen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Vesnu Publications
2012-05-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/1815 |