Differential Upregulation of Aquaporin-4 mRNA Expression in Reactive Astrocytes after Brain Injury: Potential Role in Brain Edema

Astrocytes and aquaporin-4 (AQP4) play a significant role in brain ion homeostasis. Consequently the regulation of AQP4 mRNA in the CNS after different neurological insults was of interest. A single intrastriatal injection of ringer or quinolinic acid strongly induced AQP4 mRNA in the striatum, spec...

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Bibliographic Details
Main Authors: M.L. Vizuete, J.L. Venero, C. Vargas, A.A. Ilundáin, M. Echevarra, A. Machado, J. Cano
Format: Article
Language:English
Published: Elsevier 1999-08-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996199902462