Effects of Diagnostic Errors in Pattern Differentiation and Acupuncture Prescription: A Single-Blinded, Interrater Agreement Study

• Main Authors: Ingrid Jardim de Azeredo Souza Oliveira, Arthur de Sá Ferreira
• Format: Article
• Language: English
• Published: Hindawi Limited 2015-01-01
• Series: Evidence-Based Complementary and Alternative Medicine
• Online Access: http://dx.doi.org/10.1155/2015/469675
• ISSN: 1741-427X; 1741-4288

This study compared the interrater agreement for pattern differentiation and acupoints prescription between two groups of human patients simulated with different diagnostic outcomes. Patients were simulated using a dataset about zangfu patterns and separated into groups (n=30 each) according to the diagnostic outcome determined by a computational model. A questionnaire with 90 patients was delivered to 6 TCM experts (4-year minimal of clinic experience) who were asked to indicate a single pattern (among 73) and 8 acupoints (among 378). Interrater agreement was higher for pattern differentiation than for acupuncture prescription. Interrater agreement on pattern differentiation was slight for both groups with correct (Light’s κ=0.167, 95% CI = [0.108; 0.254]) and incorrect diagnosis (Light’s κ=0.190, 95% CI = [0.120; 0.286]). Interrater agreement on acupuncture prescription was slight for both groups of correct (ι=0.029, 95% CI = [0.015; 0.057]) and incorrect diagnosis (ι=0.040, 95% CI = [0.023; 0.058], P=0.075). Diagnostic performance of raters yielded the following: accuracy = 60.9%, sensitivity = 21.7%, and specificity = 100%. An overall improvement in the interrater agreement and diagnostic accuracy was observed when the data were analyzed using the internal systems instead of the pattern’s labels.