Fibrocystin is Essential to Cellular Control of Adhesion and Epithelial Morphogenesis

Fibrocystin is Essential to Cellular Control of Adhesion and Epithelial Morphogenesis

Mutations of the <i>Pkhd1</i> gene cause autosomal recessive polycystic kidney disease (ARPKD). <i>Pkhd1</i> encodes fibrocystin/polyductin (FPC), a ciliary type I membrane protein of largely unknown function, suggested to affect adhesion signaling of cells. Contributions of...

Full description

Bibliographic Details
Main Authors: Wolfgang H. Ziegler, Birga Soetje, Lisa P. Marten, Jana Wiese, Mithila Burute, Dieter Haffner
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic kidney disease
fibrocystin
adhesion signaling
epithelial polarity
lumen formation
Online Access:https://www.mdpi.com/1422-0067/21/14/5140

Similar Items

Similar Items