Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin

Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin

<p>Abstract</p> <p>Background</p> <p>High resistance to drug is taken as a characteristic of human tumors, which is usually mediated by multidrug resistance-associated genes. ABCC2, an ATP-binding cassette multidrug resistance transporter, is found to be expressed in a...

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Bibliographic Details
Main Authors: Xie Wei, Liu Teng, Li Xin, Wang Shuang, Liu Zhen, Fang Wei, Xie Si, Yao Kai
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/55

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