CryoEM reveals the stochastic nature of individual ATP binding events in a group II chaperonin

The mechanism by which chaperonins coordinate ATP utilization in their multiple subunits remains unclear. Here, the authors employ an approach that uses cryo-EM single particle analysis to track the number and distribution of nucleotides bound to each subunit in the homo-oligomeric MmCpn archaeal ch...

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Bibliographic Details
Main Authors: Yanyan Zhao, Michael F. Schmid, Judith Frydman, Wah Chiu
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25099-0

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