Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis

Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis

OBJECTIVE: In this study, we sought to investigate the dynamic changes in the levels of TNF-α, IL-1β and LPS in the gingival crevicular fluid (GCF) in a rat model of diabetes mellitus (DM) and periodontitis (PD). Additionally, we evaluated alveolar bone loss and the histopathological response associ...

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Main Authors: Zhu-Ling Jiang, Yu-Qiong Cui, Rui Gao, Ying Li, Zhao-Chen Fu, Bin Zhang, Cheng-Chao Guan
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-130974
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spelling doaj-8c371d89281441969de1ef602817e52d2020-11-24T22:58:03ZengHindawi LimitedDisease Markers0278-02401875-86302013-01-0134529530410.3233/DMA-130974Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and PeriodontitisZhu-Ling Jiang0Yu-Qiong Cui1Rui Gao2Ying Li3Zhao-Chen Fu4Bin Zhang5Cheng-Chao Guan6Department of Implantology, the 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, ChinaDepartment of Implantology, the 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, ChinaDepartment of Orthodontics, the 1st Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, ChinaDepartment of Implantology, the 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, ChinaDepartment of Oral and Maxillofacial Surgery, the 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, ChinaDepartment of Implantology, the 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, ChinaDepartment of Implantology, the 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, ChinaOBJECTIVE: In this study, we sought to investigate the dynamic changes in the levels of TNF-α, IL-1β and LPS in the gingival crevicular fluid (GCF) in a rat model of diabetes mellitus (DM) and periodontitis (PD). Additionally, we evaluated alveolar bone loss and the histopathological response associated with experimental diabetes mellitus and experimental periodontitis.http://dx.doi.org/10.3233/DMA-130974
collection DOAJ
language English
format Article
sources DOAJ
author Zhu-Ling Jiang
Yu-Qiong Cui
Rui Gao
Ying Li
Zhao-Chen Fu
Bin Zhang
Cheng-Chao Guan
spellingShingle Zhu-Ling Jiang
Yu-Qiong Cui
Rui Gao
Ying Li
Zhao-Chen Fu
Bin Zhang
Cheng-Chao Guan
Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis
Disease Markers
author_facet Zhu-Ling Jiang
Yu-Qiong Cui
Rui Gao
Ying Li
Zhao-Chen Fu
Bin Zhang
Cheng-Chao Guan
author_sort Zhu-Ling Jiang
title Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis
title_short Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis
title_full Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis
title_fullStr Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis
title_full_unstemmed Study of TNF-α, IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis
title_sort study of tnf-α, il-1β and lps levels in the gingival crevicular fluid of a rat model of diabetes mellitus and periodontitis
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2013-01-01
description OBJECTIVE: In this study, we sought to investigate the dynamic changes in the levels of TNF-α, IL-1β and LPS in the gingival crevicular fluid (GCF) in a rat model of diabetes mellitus (DM) and periodontitis (PD). Additionally, we evaluated alveolar bone loss and the histopathological response associated with experimental diabetes mellitus and experimental periodontitis.
url http://dx.doi.org/10.3233/DMA-130974
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