Insights into GABAAergic system alteration in Huntington's disease

Huntington's disease (HD) is an autosomal dominant progressive neurodegenerative disease that is characterized by a triad of motor, psychiatric and cognitive impairments. There is still no effective therapy to delay or halt the disease progress. The striatum and cortex are two particularly affe...

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Bibliographic Details
Main Authors: Yi-Ting Hsu, Ya-Gin Chang, Yijuang Chern
Format: Article
Language:English
Published: The Royal Society 2018-12-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180165