Broccoli Fluorets: Split Aptamers as a User-Friendly Fluorescent Toolkit for Dynamic RNA Nanotechnology

Broccoli Fluorets: Split Aptamers as a User-Friendly Fluorescent Toolkit for Dynamic RNA Nanotechnology

RNA aptamers selected to bind fluorophores and activate their fluorescence offer a simple and modular way to visualize native RNAs in cells. Split aptamers which are inactive until the halves are brought within close proximity can become useful for visualizing the dynamic actions of RNA assemblies a...

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Bibliographic Details
Main Authors: Morgan Chandler, Tatiana Lyalina, Justin Halman, Lauren Rackley, Lauren Lee, Dylan Dang, Weina Ke, Sameer Sajja, Steven Woods, Shrija Acharya, Elijah Baumgarten, Jonathan Christopher, Emman Elshalia, Gabriel Hrebien, Kinzey Kublank, Saja Saleh, Bailey Stallings, Michael Tafere, Caryn Striplin, Kirill A. Afonin
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
RNA nanotechnology
aptamer
Broccoli
dynamic nanoparticles
conditional activation
Online Access:https://www.mdpi.com/1420-3049/23/12/3178

Internet

https://www.mdpi.com/1420-3049/23/12/3178

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