EGFR/c-Met and mTOR signaling are predictors of survival in non-small cell lung cancer

EGFR/c-Met and mTOR signaling are predictors of survival in non-small cell lung cancer

Background: EGFR/c-Met activation/amplification and co-expression, mTOR upregulation/activation, and Akt/Wnt signaling upregulation have been individually associated with more aggressive disease and characterized as potential prognostic markers for lung cancer patients. Methods: Tumors obtained from...

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Main Authors: Zachary D Crees, Caleb Shearrow, Leo Lin, Jennifer Girard, Kavin Arasi, Aayush Bhoraskar, Joseph Berei, Adam Eckburg, Austin D. Anderson, Christian Garcia, Ariana Munger, Sunil Palani, Thomas J Smith, Shylendra B Sreenivassappa, Connie Vitali, Odile David, Neelu Puri
Format: Article
Language:English
Published: SAGE Publishing 2020-09-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835920953731

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