Hypervalent iodine/TEMPO-mediated oxidation in flow systems: a fast and efficient protocol for alcohol oxidation

Hypervalent iodine/TEMPO-mediated oxidation in flow systems: a fast and efficient protocol for alcohol oxidation

Hypervalent iodine(III)/TEMPO-mediated oxidation of various aliphatic, aromatic and allylic alcohols to their corresponding carbonyl compounds was successfully achieved by using microreactor technology. This method can be used as an alternative for the oxidation of various alcohols achieving excelle...

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Bibliographic Details
Main Authors: Nida Ambreen, Ravi Kumar, Thomas Wirth
Format: Article
Language:English
Published: Beilstein-Institut 2013-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
alcohols
carbonyl compounds
flow chemistry
microreactor
oxidation
Online Access:https://doi.org/10.3762/bjoc.9.162
Description
Summary:Hypervalent iodine(III)/TEMPO-mediated oxidation of various aliphatic, aromatic and allylic alcohols to their corresponding carbonyl compounds was successfully achieved by using microreactor technology. This method can be used as an alternative for the oxidation of various alcohols achieving excellent yields and selectivities in significantly shortened reaction times.
ISSN:1860-5397

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