Fission yeast condensin contributes to interphase chromatin organization and prevents transcription-coupled DNA damage

Fission yeast condensin contributes to interphase chromatin organization and prevents transcription-coupled DNA damage

Abstract Background Structural maintenance of chromosomes (SMC) complexes are central organizers of chromatin architecture throughout the cell cycle. The SMC family member condensin is best known for establishing long-range chromatin interactions in mitosis. These compact chromatin and create mechan...

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Bibliographic Details
Main Authors: Yasutaka Kakui, Christopher Barrington, David J. Barry, Tereza Gerguri, Xiao Fu, Paul A. Bates, Bhavin S. Khatri, Frank Uhlmann
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Genome Biology
Subjects:
Condensin
Chromosome architecture
Interphase chromatin
Transcription
DNA damage
Polymer physics
Online Access:http://link.springer.com/article/10.1186/s13059-020-02183-0

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