Germ cell development in the postnatal testis: the key to prevent malignancy in cryptorchidism?

To permit normal postnatal germ cell development, the mammalian testis undergoes a complex, multi-staged process of descent to the scrotum. Failure of any part of this process leads to congenital cryptorchidism, wherein the malpositioned testis finds itself at the wrong temperature after birth, whi...

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Bibliographic Details
Main Authors: John Medwyn Hutson, Ruili eLi, Bridget R Southwell, Bodil ePetersen, Joergen eThorup, Dina eCortes
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00176/full