Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163+ Macrophages

Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163+ Macrophages

Intraplaque hemorrhage causes adaptive remodelling of macrophages towards a protective phenotype specialized towards handling iron and lipid overload, denoted Mhem. The Mhem phenotype expresses elevated levels of hemoglobin (Hb) scavenger receptor, CD163, capable of endocytosing pro-oxidant free Hb...

Full description

Bibliographic Details
Main Authors:	R. Clive Landis, Pandelis Philippidis, Jan Domin, Joseph J. Boyle, Dorian O. Haskard
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	International Journal of Inflammation
Online Access:	http://dx.doi.org/10.1155/2013/980327

Similar Items

Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation
by: Betsy J. Evans, et al.
Published: (2013-01-01)

The role of the monocyte/macrophage in the resolution of the systemic inflammatory response to cardiopulmonary bypass surgery
by: Philippidis, Pandelis
Published: (2007)

The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging
by: Jens Haugbølle Thomsen, et al.
Published: (2013-01-01)

The intrathecal CD163-haptoglobin-hemoglobin scavenging system in subarachnoid hemorrhage
by: Galea, James, et al.
Published: (2012)

Targeting of CD163<sup>+</sup> Macrophages in Inflammatory and Malignant Diseases
by: Maria K. Skytthe, et al.
Published: (2020-07-01)

Soluble CD163 Levels and CD163+CD14+ Monocyte/Macrophage Counts in Patients with Asthma
by: Yue Zhi, et al.
Published: (2018-09-01)

PPAR-γ Promotes Hematoma Clearance through Haptoglobin-Hemoglobin-CD163 in a Rat Model of Intracerebral Hemorrhage
by: Gaiqing Wang, et al.
Published: (2018-01-01)

Unique Contribution of Haptoglobin and Haptoglobin Genotype in Aneurysmal Subarachnoid Hemorrhage
by: Spiros L. Blackburn, et al.
Published: (2018-05-01)

Drug Trafficking into Macrophages via the Endocytotic Receptor CD163
by: Jonas Heilskov Graversen, et al.
Published: (2015-06-01)

Macrophage CD163 expression is neuroprotective in subarachnoid hemorrhage patients
by: Chen, Ruiya
Published: (2016)

The clinical significance of the CD163+ and CD68+ macrophages in patients with hepatocellular carcinoma.
by: Ling-Qun Kong, et al.
Published: (2013-01-01)

Distinct Profiles of CD163-Positive Macrophages in Idiopathic Interstitial Pneumonias
by: Masahiro Yamashita, et al.
Published: (2018-01-01)

Immune-to-brain signalling: the role of cerebral CD163-positive macrophages
by: Galea, Ian, et al.
Published: (2008)

Prognostic significance of CD163+ tumor-associated macrophages in colorectal cancer
by: Tao Xue, et al.
Published: (2021-06-01)

Macrophage Activation Markers, CD163 and CD206, in Acute-on-Chronic Liver Failure
by: Marlene Christina Nielsen, et al.
Published: (2020-05-01)

CD163 versus CD68 in tumor associated macrophages of classical hodgkin lymphoma
by: Harris Jonathan A, et al.
Published: (2012-01-01)

CD47 expression and CD163+ macrophages correlated with prognosis of pancreatic neuroendocrine tumor
by: Rami Imam, et al.
Published: (2021-03-01)

The Role of Haptoglobin Genotypes in Chagas Disease
by: Ninomar Mundaray Fernández, et al.
Published: (2014-01-01)

Macrophage Activation Markers, Soluble CD163 and Mannose Receptor, in Liver Fibrosis
by: Rasmus Hvidbjerg Gantzel, et al.
Published: (2021-01-01)

CD163 and CCR7 as markers for macrophage polarisation in lung cancer microenvironment
by: Iwona Kwiecień, et al.
Published: (2020-01-01)

Regular Training Increases sTWEAK and Its Decoy Receptor sCD163–Does Training Trigger the sTWEAK/sCD163-Axis to Induce an Anti-Inflammatory Effect?
by: Robert Schönbauer, et al.
Published: (2020-06-01)

Antibody-Directed Glucocorticoid Targeting to CD163 in M2-type Macrophages Attenuates Fructose-Induced Liver Inflammatory Changes
by: Pia Svendsen, et al.
Published: (2017-03-01)

High Counts of CD68+ and CD163+ Macrophages in Mantle Cell Lymphoma Are Associated With Inferior Prognosis
by: Philippa Li, et al.
Published: (2021-08-01)

PKM2 Expression and Elevated CD163 in Macrophage Synergistically Promote Osteosarcoma Progression
by: TAN Wenfu, et al.
Published: (2019-12-01)

Relationship Between sCD163 and mCD163 and Their Implication in the Detection and Typing of Leprosy
by: Farag AGA, et al.
Published: (2020-06-01)

Haptoglobins and hemoglobin-haptoglobin complexes
by: Malchy, Barry L.
Published: (2011)

Tongue Cancer Cell-Derived CCL20 Induced by Interaction With Macrophages Promotes CD163 Expression on Macrophages
by: Manabu Shigeoka, et al.
Published: (2021-06-01)

Haptoglobin genotypes predict the survival of patients with colorectal cancer
by: Hung-Chih, et al.
Published: (2012)

The Ratio of CD86+/CD163+ Macrophages Predicts Postoperative Recurrence in Stage II-III Colorectal Cancer
by: Guozeng Xu, et al.
Published: (2021-08-01)

Overexpression of CD163, CD204 and CD206 on alveolar macrophages in the lungs of patients with severe chronic obstructive pulmonary disease.
by: Yoichiro Kaku, et al.
Published: (2014-01-01)

CD163+ macrophages infiltration correlates with the immunosuppressive cytokine interleukin 10 expression in tongue leukoplakia
by: Manabu Shigeoka, et al.
Published: (2019-12-01)

Soluble CD163 as a marker of macrophage activity in newly diagnosed patients with multiple sclerosis.
by: Morten Stilund, et al.
Published: (2014-01-01)

CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation
by: Fabriek, Babs O., et al.
Published: (2005)

High Numbers of CD163-Positive Macrophages in the Fibrotic Region of Exuberant Granulation Tissue in Horses
by: Charis Du Cheyne, et al.
Published: (2021-09-01)

CD163 and its role in inflammation
by: Lech Chyczewski, et al.
Published: (2011-10-01)

Tumor-Associated CD68+, CD163+, and MARCO+ Macrophages as Prognostic Biomarkers in Patients With Treatment-Naïve Gastroesophageal Adenocarcinoma
by: Martin Jeremiasen, et al.
Published: (2020-10-01)

PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients
by: Ya. O. Yemchenko, et al.
Published: (2020-01-01)

CD163 deficiency facilitates lipopolysaccharide‐induced inflammatory responses and endotoxin shock in mice
by: Yukio Fujiwara, et al.
Published: (2020-01-01)

Lesional accumulation of CD163-expressing cells in the gut of patients with inflammatory bowel disease.
by: Eleonora Franzè, et al.
Published: (2013-01-01)

Determination of Haptoglobin Genotype in an Iranian Population with Idiopathic Generalized Epilepsy
by: Sukaina Al-balaghee, et al.
Published: (2015-05-01)

Cannot write session to /tmp/vufind_sessions/sess_673ci1cemmv5qi53qp1bqukuu8