Cancer-Specific Biomarker hNQO1-Activatable Fluorescent Probe for Imaging Cancer Cells In Vitro and In Vivo

Cancer-Specific Biomarker hNQO1-Activatable Fluorescent Probe for Imaging Cancer Cells In Vitro and In Vivo

Human NAD(P)H quinone oxidoreductase-1 (hNQO1) is an important cancer-related biomarker, which shows significant overexpression in malignant cells. Developing an effective method for detecting NQO1 activity with high sensitivity and selectivity in tumors holds a great potential for cancer diagnosis,...

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Bibliographic Details
Main Authors: Surendra Reddy Punganuru, Hanumantha Rao Madala, Viswanath Arutla, Kalkunte S. Srivenugopal
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cancers
Subjects:
fluorescent probe
cancer biomarker
tumor diagnosis
cancer imaging
NAD(P)H quinone oxidoreductase 1
large Stokes shift
dicyanoisophorone
Online Access:https://www.mdpi.com/2072-6694/10/12/470

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https://www.mdpi.com/2072-6694/10/12/470

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