Targeted Approaches Applied to Uncommon Diseases: A Case of Salivary Duct Carcinoma Metastatic to the Brain Treated with the Multikinase Inhibitor Neratinib

Targeted Approaches Applied to Uncommon Diseases: A Case of Salivary Duct Carcinoma Metastatic to the Brain Treated with the Multikinase Inhibitor Neratinib

Salivary duct carcinoma is a rare malignancy associated with hormone receptor and human epidermal growth factor receptor 2 (HER2) overexpression. Local surgical control is the cornerstone of therapy, but a subset of patients develops metastatic disease portending a poor prognosis and limited managem...

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Bibliographic Details
Main Authors: Karl R. Sorenson, Guilherme Piovezani Ramos, Jose Caetano Villasboas Bisneto, Katharine Price
Format: Article
Language:English
Published: Karger Publishers 2017-08-01
Series:Case Reports in Oncology
Subjects:
Salivary duct carcinoma
Intracranial metastasis
Neratinib
Human epidermal growth factor receptor 2
Targeted therapy
Online Access:http://www.karger.com/Article/FullText/479499

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