A candidate DNA vaccine encoding a fusion protein of porcine complement C3d-P28 and ORF2 of porcine circovirus type 2 induces cross-protective immunity against PCV2b and PCV2d in pigs

A candidate DNA vaccine encoding a fusion protein of porcine complement C3d-P28 and ORF2 of porcine circovirus type 2 induces cross-protective immunity against PCV2b and PCV2d in pigs

Abstract Background Porcine circovirus type 2 (PCV2) is an economically important viral pathogen for swine industry worldwide. However, current PCV2 vaccines provide incomplete protection against the PCV2d, which has recently emerged as the predominant pathogenic form of PCV2. Methods To develop a n...

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Bibliographic Details
Main Authors: Zhumei Hou, Honghua Wang, Yanni Feng, Qingwang Li, Junwei Li
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Virology Journal
Subjects:
DNA vaccine
C3d-P28
ORF2
PCV2b, PCV2d
Online Access:http://link.springer.com/article/10.1186/s12985-019-1156-2

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