The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways

Abstract Background Myogenesis is a highly regulated process ending with the formation of myotubes, the precursors of skeletal muscle fibers. Differentiation of myoblasts into myotubes is controlled by myogenic regulatory factors (MRFs) that act as terminal effectors of signaling cascades involved i...

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Bibliographic Details
Main Authors: L. Coudert, A. Osseni, Y. G. Gangloff, L. Schaeffer, P. Leblanc
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-021-01091-4