Synthesis of Dextran–Phenoxodiol and Evaluation of Its Physical Stability and Biological Activity
Phenoxodiol, an isoflavene anti-tumor agent, was conjugated on the polysaccharide dextran using immobilized laccase as biocatalyst. The success of the enzymatic conjugation was determined by UV-vis spectrophotometry and its functionalization degree was assessed by 1H NMR and was found to be 3.25 mg...
Main Authors: | Eugene M. H. Yee, Giuseppe Cirillo, Miriam B. Brandl, David StC Black, Orazio Vittorio, Naresh Kumar |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-08-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2019.00183/full |
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