Peptide hydrogels – versatile matrices for 3D cell culture in cancer medicine

Peptide hydrogels – versatile matrices for 3D cell culture in cancer medicine

Traditional two-dimensional (2D) cell culture systems have contributed tremendously to our understanding of cancer biology but have significant limitations in mimicking in vivo conditions such as the tumor microenvironment. In vitro, three-dimensional (3D) cell culture models represent a more accura...

Full description

Bibliographic Details
Main Authors:	Peter eWorthington, Darrin John Pochan, Sigrid A Langhans
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-04-01
Series:	Frontiers in Oncology
Subjects:	Hydrogel Cancer Matrix three-dimensional cell culture Functionalization
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00092/full

Similar Items

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning
by: Sigrid A. Langhans
Published: (2018-01-01)

SUPERCRITICAL FLUID TREATMENT OF THREE-DIMENSIONAL HYDROGEL MATRICES, COMPOSED OF CHITOSAN DERIVATIVES
by: P. S. Timashev, et al.
Published: (2016-11-01)

HYDROGELS AND THEIR APLICATION AREAS
by: AÇIKEL Safiye Meriç, et al.
Published: (2016-05-01)

Techniques for RNA extraction from cells cultured in starPEG–heparin hydrogels
by: Anna Jaeschke, et al.
Published: (2021-06-01)

Three-Dimensional Calcium Alginate Hydrogel Assembly via TiOPc-Based Light-Induced Controllable Electrodeposition
by: Yang Liu, et al.
Published: (2017-06-01)

Three-Dimensional Graphene-Based Composite Hydrogel Materials for Flexible Supercapacitor Electrodes
by: Enping Lai, et al.
Published: (2019-10-01)

Cell Guidance by 3D-Gradients in Hydrogel Matrices: Importance for Biomedical Applications
by: Tessa Lühmann, et al.
Published: (2009-08-01)

Polymerizable Microsphere-Induced High Mechanical Strength of Hydrogel Composed of Acrylamide
by: Zhiyong Wang, et al.
Published: (2018-05-01)

Mechanically tuned 3 dimensional hydrogels support human mammary fibroblast growth and viability
by: Kathryn Woods, et al.
Published: (2017-12-01)

Angiogenic Potential in Biological Hydrogels
by: Maria Vittoria Giraudo, et al.
Published: (2020-10-01)

Hydrogels as Extracellular Matrix Analogs
by: Eva C. González-Díaz, et al.
Published: (2016-08-01)

Paracrine study of adipose tissue-derived mesenchymal stem cells (ADMSCs) in a self-assembling nano-polypeptide hydrogel environment
by: Ling Jianmin, et al.
Published: (2021-08-01)

Preparation of EpH4 and 3T3L1 cells aggregates incorporating gelatin hydrogel microspheres for a cell condition improvement
by: Shuhei Tajima, et al.
Published: (2017-06-01)

Injectable Alginate-Peptide Composite Hydrogel as a Scaffold for Bone Tissue Regeneration
by: Moumita Ghosh, et al.
Published: (2019-04-01)

Assessment of Mechanical and Tribological Properties of Alginate-polyacrylamide Hydrogel Matrix Composites As Minimally Invasive Cartilage Implants
by: Arjmandi, Mohammadreza
Published: (2019)

Programming Multistate Aggregation‐Induced Emissive Polymeric Hydrogel into 3D Structures for On‐Demand Information Decryption and Transmission
by: Huiyu Qiu, et al.
Published: (2021-06-01)

Fluid–Structure Interaction Analysis of Perfusion Process of Vascularized Channels within Hydrogel Matrix Based on Three-Dimensional Printing
by: Shuai Yang, et al.
Published: (2020-08-01)

Dendrimers and Dendrons as Versatile Building Blocks for the Fabrication of Functional Hydrogels
by: Sadik Kaga, et al.
Published: (2016-04-01)

Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus
by: Wei Chen, et al.
Published: (2020-01-01)

Smart Hydrogels in Tissue Engineering and Regenerative Medicine
by: Somasundar Mantha, et al.
Published: (2019-10-01)

Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture
by: Girdhari Rijal, et al.
Published: (2018-09-01)

Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices
by: Gabriela Štumberger, et al.
Published: (2018-12-01)

Hydrogels Derivatized With Cationic Moieties or Functional Peptides as Efficient Supports for Neural Stem Cells
by: Kristin Glotzbach, et al.
Published: (2020-05-01)

Responsive Hydrogels from Associative Block Copolymers: Physical Gelling through Polyion Complexation
by: Christine M. Papadakis, et al.
Published: (2017-01-01)

Lower bound of four-dimensional Hausdorff matrices
by: Gholamreza Talebi
Published: (2019-03-01)

Electrochemical Hydrogel Lithography of Calcium-Alginate Hydrogels for Cell Culture
by: Fumisato Ozawa, et al.
Published: (2016-08-01)

Natural and Synthetic Biomaterials for Engineering Multicellular Tumor Spheroids
by: Advika Kamatar, et al.
Published: (2020-10-01)

Composite System of 3D-Printed Polymer and Acellular Matrix Hydrogel to Repair Temporomandibular Joint Disc
by: Ping Yi, et al.
Published: (2021-03-01)

Alginate Bioconjugate and Graphene Oxide in Multifunctional Hydrogels for Versatile Biomedical Applications
by: Giuseppe Cirillo, et al.
Published: (2021-03-01)

3D Cell Culture in Alginate Hydrogels
by: Therese Andersen, et al.
Published: (2015-03-01)

Morphological analysis of isolated rat pancreatic islets cultured under standard culture technique and with biopolymer microstructured collagen‑containing hydrogel
by: L. A. Kirsanova, et al.
Published: (2017-06-01)

Multifunctional soft machines based on stimuli-responsive hydrogels: from freestanding hydrogels to smart integrated systems
by: M. Ding, et al.
Published: (2020-12-01)

T Cell Migration in Three-dimensional ExtracellularMatrix: Guidance by Polarity and Sensations
by: Peter Friedl, et al.
Published: (2000-01-01)

Moving Myeloid Leukemia Drug Discovery Into the Third Dimension
by: Donna M. Cartledge Wolf, et al.
Published: (2019-07-01)

Functional cellulose-based hydrogels as extracellular matrices for tissue engineering
by: Sayan Deb Dutta, et al.
Published: (2019-06-01)

A peptidic hydrogel that may behave as a “Trojan Horse”
by: Nicola Castellucci, et al.
Published: (2013-02-01)

A Novel Composite Hydrogel Composed of Formic Acid-Decellularized Pepsin-Soluble Extracellular Matrix Hydrogel and Sacchachitin Hydrogel as Wound Dressing to Synergistically Accelerate Diabetic Wound Healing
by: Chien-Ming Hsieh, et al.
Published: (2020-06-01)

Research progress in decellularized extracellular matrix-derived hydrogels
by: Wenhui Zhang, et al.
Published: (2021-12-01)

Extracellular Matrix-Derived Hydrogels as Biomaterial for Different Skeletal Muscle Tissue Replacements
by: Daniele Boso, et al.
Published: (2020-05-01)

A Diffusion-Reaction Model for Predicting Enzyme-Mediated Dynamic Hydrogel Stiffening
by: Hung-Yi Liu, et al.
Published: (2019-03-01)