MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth

MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth

Abstract Background Anoikis resistance has been demonstrated to facilitate distant metastases of cancers. MicroRNA-133b (miR-133b) is found to be down-regulated in various tumors, including esophageal squamous cell carcinoma (ESCC), and closely correlates with the malignant phenotype of ESCC. This s...

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Bibliographic Details
Main Authors: Jin-Feng Zhu, Yi Liu, He Huang, Li Shan, Zhi-Gang Han, Jun-Yuan Liu, Ying-Long Li, Xiang Dong, Wei Zeng
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Cancer Cell International
Subjects:
Esophageal squamous cell carcinoma
miR-133b
Epidermal growth factor receptor
Metastases
Anoikis
Anchorage-independent growth
Online Access:http://link.springer.com/article/10.1186/s12935-018-0684-y

Internet

http://link.springer.com/article/10.1186/s12935-018-0684-y

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