The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours

The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours

Abstract Background Use of cyclin D1 (CCND1) gene amplification as a breast cancer biomarker has been hampered by conflicting assessments of the relationship between cyclin D1 protein levels and patient survival. Here, we aimed to clarify its prognostic and treatment predictive potential through com...

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Bibliographic Details
Main Authors: Arian Lundberg, Linda S. Lindström, Jingmei Li, J. Chuck Harrell, Eva Darai-Ramqvist, Emmanouil G. Sifakis, Theodoros Foukakis, Charles M. Perou, Kamila Czene, Jonas Bergh, Nicholas P. Tobin
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Breast Cancer Research
Subjects:
CCND1 gene amplification
Gene expression
Breast cancer
PAM50
Luminal A
CDK4/6
Online Access:http://link.springer.com/article/10.1186/s13058-019-1121-4

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