A statistical framework for detecting mislabeled and contaminated samples using shallow-depth sequence data

Abstract Background Researchers typically sequence a given individual multiple times, either re-sequencing the same DNA sample (technical replication) or sequencing different DNA samples collected on the same individual (biological replication) or both. Before merging the data from these replicate s...

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Bibliographic Details
Main Authors: Ariel W. Chan, Amy L. Williams, Jean-Luc Jannink
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2512-8

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