Production of human recombinant neurotrophins for biomedical studies

The genes of nerve growth factor (NGF), brain neurotrophic factor (BDNF) and human neurotrophic factor 3 (NT-3) were cloned and expressed in Escherichia coli. Methods of purification and renaturation of the proneurotrophins were developed. It was shown that the recombinant pro-NGF, pro-BDNF and pro-...

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Bibliographic Details
Main Authors: L. M. Rafieva, D. R. Safina, I. V. Demidyuk, S. V. Kostrov
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2011-04-01
Series:Тонкие химические технологии
Subjects:
Online Access:https://www.finechem-mirea.ru/jour/article/view/862