Lycopene relieves AFB1-induced liver injury through enhancing hepatic antioxidation and detoxification potential with Nrf2 activation

To evaluate the chemoprotective effect and mechanism of lycopene (LYC) on aflatoxin B1 (AFB1)-induced liver injury, forty-eight male mice were randomly allocated and treated with LYC (5 mg/kg) and/or AFB1 (0.75 mg/kg) by intragastric administration for 30 days. We found that LYC reduced AFB1-DNA add...

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Bibliographic Details
Main Authors: Feibo Xu, Kaiyuan Yu, Hongyan Yu, Peiyan Wang, Miao Song, Chunyu Xiu, Yanfei Li
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Journal of Functional Foods
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Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617306369