Cangrelor ameliorates CLP-induced pulmonary injury in sepsis by inhibiting GPR17

Cangrelor ameliorates CLP-induced pulmonary injury in sepsis by inhibiting GPR17

Abstract Background Sepsis is a common complication of severe wound injury and infection, with a very high mortality rate. The P2Y12 receptor inhibitor, cangrelor, is an antagonist anti-platelet drug. Methods In our study, we investigated the protective mechanisms of cangrelor in CLP-induced pulmona...

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Bibliographic Details
Main Authors: Qiancheng Luo, Rui Liu, Kaili Qu, Guorong Liu, Min Hang, Guo Chen, Lei Xu, Qinqin Jin, Dongfeng Guo, Qi Kang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:European Journal of Medical Research
Subjects:
Sepsis
Inflammation
Cangrelor
Platelet
GPR17
Online Access:https://doi.org/10.1186/s40001-021-00536-4

Internet

https://doi.org/10.1186/s40001-021-00536-4

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