Structures of Cyclic Organosulfur Compounds From Garlic (Allium sativum L.) Leaves

• Main Authors: Masashi Fukaya, Seikou Nakamura, Hitoshi Hayashida, Daisuke Noguchi, Souichi Nakashima, Taichi Yoneda, Hisashi Matsuda
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2020-04-01
• Series: Frontiers in Chemistry
• Subjects: Allium sativum L.; garlic; organosulfur compound; foliogarlic disulfane; foliogarlic trisulfane
• Online Access: https://www.frontiersin.org/article/10.3389/fchem.2020.00282/full

Five new cyclic organosulfur compounds, foliogarlic disulfanes A1 (1), A2 (2), and A3 (3) and foliogarlic trisulfane A1 (4) and A2 (5), were isolated from the leaves of Allium sativum (garlic). The chemical structures of these compounds were elucidated on the basis of physicochemical evidence including Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). Compounds 1–5 were obtained as complex compounds with disulfane or trisulfane and tetrahydro-2H-difuro[3,2-b:2′,3′-c]furan-5(5aH)-one. In addition, the hypothetical biosynthetic pathways of these compounds were suggested.