Regional transcriptome analysis of AMPA and GABAA receptor subunit expression generates E/I signatures of the human brain
Abstract Theoretical and experimental work has demonstrated that excitatory (E) and inhibitory (I) currents within cortical circuits stabilize to a balanced state. This E/I balance, observed from single neuron to network levels, has a fundamental role in proper brain function and its impairment has...
Main Authors: | Kevin Shen, Tommaso Zeppillo, Agenor Limon |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-68165-1 |
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