Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance

This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disea...

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Main Authors:	Anna V. Bocharova, Kseniya V. Vagaitseva, Oksana A. Makeeva, Andrey V. Marusin, Vadim A. Stepanov
Format:	Article
Language:	English
Published:	Elsevier 2018-02-01
Series:	Data in Brief
Online Access:	http://www.sciencedirect.com/science/article/pii/S235234091730714X

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spelling	doaj-8bad5f16c4fe45f9ab07a5ec9e7ff4f52020-11-25T02:19:00ZengElsevierData in Brief2352-34092018-02-0116775779Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performanceAnna V. Bocharova0Kseniya V. Vagaitseva1Oksana A. Makeeva2Andrey V. Marusin3Vadim A. Stepanov4Laboratory of Evolutionary Genetics, Institute of Medical Genetics, Tomsk National Medical Research Center, Tomsk, RussiaLaboratory of Evolutionary Genetics, Institute of Medical Genetics, Tomsk National Medical Research Center, Tomsk, Russia; Laboratory of Human Ontogenetics, Tomsk State University, Tomsk, RussiaLaboratory of Evolutionary Genetics, Institute of Medical Genetics, Tomsk National Medical Research Center, Tomsk, Russia; Nebbiolo Center for Clinical Trials, Tomsk, RussiaLaboratory of Evolutionary Genetics, Institute of Medical Genetics, Tomsk National Medical Research Center, Tomsk, RussiaLaboratory of Evolutionary Genetics, Institute of Medical Genetics, Tomsk National Medical Research Center, Tomsk, Russia; Laboratory of Human Ontogenetics, Tomsk State University, Tomsk, Russia; Corresponding author at: Laboratory of Evolutionary Genetics, Institute of Medical Genetics, Tomsk National Medical Research Center, Tomsk, Russia.This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disease and cognitive functions in genome-wide and candidate genes association studies. Cognitive performance in sample set was estimated by the Montreal Cognitive Assessment (MoCA). The frequencies of alleles, genotypes and haplotypes of two SNPs were calculated in 3 groups: total sample set, sample set with MoCA score less than 21 (the first quartile) and group with MoCA score more than 24 (the fourth quartile). Keywords: CLU, Cognitive performance, MoCa, Russian population, Elderly, Alzheimer's diseasehttp://www.sciencedirect.com/science/article/pii/S235234091730714X
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Anna V. Bocharova Kseniya V. Vagaitseva Oksana A. Makeeva Andrey V. Marusin Vadim A. Stepanov
spellingShingle	Anna V. Bocharova Kseniya V. Vagaitseva Oksana A. Makeeva Andrey V. Marusin Vadim A. Stepanov Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance Data in Brief
author_facet	Anna V. Bocharova Kseniya V. Vagaitseva Oksana A. Makeeva Andrey V. Marusin Vadim A. Stepanov
author_sort	Anna V. Bocharova
title	Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance
title_short	Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance
title_full	Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance
title_fullStr	Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance
title_full_unstemmed	Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance
title_sort	frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the russian elderly population categorized by cognitive performance
publisher	Elsevier
series	Data in Brief
issn	2352-3409
publishDate	2018-02-01
description	This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disease and cognitive functions in genome-wide and candidate genes association studies. Cognitive performance in sample set was estimated by the Montreal Cognitive Assessment (MoCA). The frequencies of alleles, genotypes and haplotypes of two SNPs were calculated in 3 groups: total sample set, sample set with MoCA score less than 21 (the first quartile) and group with MoCA score more than 24 (the fourth quartile). Keywords: CLU, Cognitive performance, MoCa, Russian population, Elderly, Alzheimer's disease
url	http://www.sciencedirect.com/science/article/pii/S235234091730714X
work_keys_str_mv	AT annavbocharova frequenciesofallelesgenotypesandhaplotypesoftwopolymorphismsintheclusteringeneintherussianelderlypopulationcategorizedbycognitiveperformance AT kseniyavvagaitseva frequenciesofallelesgenotypesandhaplotypesoftwopolymorphismsintheclusteringeneintherussianelderlypopulationcategorizedbycognitiveperformance AT oksanaamakeeva frequenciesofallelesgenotypesandhaplotypesoftwopolymorphismsintheclusteringeneintherussianelderlypopulationcategorizedbycognitiveperformance AT andreyvmarusin frequenciesofallelesgenotypesandhaplotypesoftwopolymorphismsintheclusteringeneintherussianelderlypopulationcategorizedbycognitiveperformance AT vadimastepanov frequenciesofallelesgenotypesandhaplotypesoftwopolymorphismsintheclusteringeneintherussianelderlypopulationcategorizedbycognitiveperformance
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Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance

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