A Tumor-Infiltration CD8+ T Cell-Based Gene Signature for Facilitating the Prognosis and Estimation of Immunization Responses in HPV+ Head and Neck Squamous Cell Cancer

A Tumor-Infiltration CD8+ T Cell-Based Gene Signature for Facilitating the Prognosis and Estimation of Immunization Responses in HPV+ Head and Neck Squamous Cell Cancer

BackgroundCD8+ T cells, which play a vital role in response to adaptive immunity, are closely related to the immunization responses to kill tumor cells. Understanding the effects exerted by tumor-infiltrated CD8+ T cells in HPV+ and HPV- head and neck squamous cell carcinoma (HNSCC) patients is crit...

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Bibliographic Details
Main Authors: Yingning Wu, Lingzhang Meng, Kai Cai, Jingjie Zhao, Siyuan He, Jiajia Shen, Qiuju Wei, Zechen Wang, Suren Sooranna, Hengguo Li, Jian Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
CD8+ T cells
HPV
immunization-correlated genes
immunization-correlated therapy
differentially expressed genes
predicted prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.749398/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.749398/full

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