Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index

Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index

Background: Women with polycystic ovary syndrome (PCOS) have an increased prevalence of insulin resistance (IR) and related disorders. Elevated serum levels of high sensitivity CRP (hs-CRP), interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) reflect low-grade chronic inflammation and have been...

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Main Authors: Nervana Samy, Maha Hashim, Magda Sayed, Mohamed Said
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2009-0627
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spelling doaj-8b889f6b51e34b71adc40f0a87432d2a2020-11-24T21:03:00ZengHindawi LimitedDisease Markers0278-02401875-86302009-01-0126416317010.3233/DMA-2009-0627Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass IndexNervana Samy0Maha Hashim1Magda Sayed2Mohamed Said3Biochemistry Department, National Research Center, Cairo, EgyptBiochemistry Department, National Research Center, Cairo, EgyptBiochemistry Department, National Research Center, Cairo, EgyptObstetrics and Gynecology Department, Faculty of medicine, Ain Shams University, Cairo, EgyptBackground: Women with polycystic ovary syndrome (PCOS) have an increased prevalence of insulin resistance (IR) and related disorders. Elevated serum levels of high sensitivity CRP (hs-CRP), interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) reflect low-grade chronic inflammation and have been associated with several insulin-resistant states; they are useful cardiovascular risk markers. The objective of this study was to investigate whether soluble inflammatory markers are altered in PCOS focusing on its relationship with obesity and indexes of insulin resistance.http://dx.doi.org/10.3233/DMA-2009-0627
collection DOAJ
language English
format Article
sources DOAJ
author Nervana Samy
Maha Hashim
Magda Sayed
Mohamed Said
spellingShingle Nervana Samy
Maha Hashim
Magda Sayed
Mohamed Said
Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index
Disease Markers
author_facet Nervana Samy
Maha Hashim
Magda Sayed
Mohamed Said
author_sort Nervana Samy
title Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index
title_short Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index
title_full Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index
title_fullStr Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index
title_full_unstemmed Clinical Significance of Inflammatory Markers in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance and Body Mass Index
title_sort clinical significance of inflammatory markers in polycystic ovary syndrome: their relationship to insulin resistance and body mass index
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2009-01-01
description Background: Women with polycystic ovary syndrome (PCOS) have an increased prevalence of insulin resistance (IR) and related disorders. Elevated serum levels of high sensitivity CRP (hs-CRP), interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) reflect low-grade chronic inflammation and have been associated with several insulin-resistant states; they are useful cardiovascular risk markers. The objective of this study was to investigate whether soluble inflammatory markers are altered in PCOS focusing on its relationship with obesity and indexes of insulin resistance.
url http://dx.doi.org/10.3233/DMA-2009-0627
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AT mahahashim clinicalsignificanceofinflammatorymarkersinpolycysticovarysyndrometheirrelationshiptoinsulinresistanceandbodymassindex
AT magdasayed clinicalsignificanceofinflammatorymarkersinpolycysticovarysyndrometheirrelationshiptoinsulinresistanceandbodymassindex
AT mohamedsaid clinicalsignificanceofinflammatorymarkersinpolycysticovarysyndrometheirrelationshiptoinsulinresistanceandbodymassindex
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