Design and evaluation of nicorandil extended-release tablet

Design and evaluation of nicorandil extended-release tablet

The aim of this study was to design and evaluate extended-release formulations of a model drug, nicorandil, in order to achieve the desired steady-state plasma concentration of drug in vivo. Simulation was employed to estimate optimum dissolution and absorption rate of nicorandil. The dissolution te...

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Bibliographic Details
Main Authors:	Ju-Young Kim, Chun-Woong Park, Beom-Jin Lee, Eun-Seok Park, Yun-Seok Rhee
Format:	Article
Language:	English
Published:	Elsevier 2015-04-01
Series:	Asian Journal of Pharmaceutical Sciences
Subjects:	Nicorandil In vitro In vivo Pharmacokinetic Extended-release
Online Access:	http://www.sciencedirect.com/science/article/pii/S1818087614000713

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