H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions

H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions

H2SO4-Silica efficiently catalyzes the three-component condensation reaction of aldehydes, 1,3-dicarbonyl compounds and urea/thiourea under solvent free conditions to afford the corresponding dihydropyrimidinones and thio-derivatives in high yields. Compared to the classical Biginelli reaction condi...

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Main Authors: Seied Ali Pourmousavi, Maryam Hasani
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/158612
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spelling doaj-8b877f38041c46aea34d358bb5c05c442020-11-24T22:12:32ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102011-01-018S1S462S46610.1155/2011/158612H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free ConditionsSeied Ali Pourmousavi0Maryam Hasani1School of Chemistry, Damghan University, Damghan-3671641167, IranSchool of Chemistry, Damghan University, Damghan-3671641167, IranH2SO4-Silica efficiently catalyzes the three-component condensation reaction of aldehydes, 1,3-dicarbonyl compounds and urea/thiourea under solvent free conditions to afford the corresponding dihydropyrimidinones and thio-derivatives in high yields. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of giving good yields and requiring short reaction times.http://dx.doi.org/10.1155/2011/158612
collection DOAJ
language English
format Article
sources DOAJ
author Seied Ali Pourmousavi
Maryam Hasani
spellingShingle Seied Ali Pourmousavi
Maryam Hasani
H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions
E-Journal of Chemistry
author_facet Seied Ali Pourmousavi
Maryam Hasani
author_sort Seied Ali Pourmousavi
title H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions
title_short H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions
title_full H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions
title_fullStr H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions
title_full_unstemmed H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions
title_sort h2so4-silica catalyzed one-pot and efficient synthesis of dihydropyrimidinones under solvent-free conditions
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2011-01-01
description H2SO4-Silica efficiently catalyzes the three-component condensation reaction of aldehydes, 1,3-dicarbonyl compounds and urea/thiourea under solvent free conditions to afford the corresponding dihydropyrimidinones and thio-derivatives in high yields. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of giving good yields and requiring short reaction times.
url http://dx.doi.org/10.1155/2011/158612
work_keys_str_mv AT seiedalipourmousavi h2so4silicacatalyzedonepotandefficientsynthesisofdihydropyrimidinonesundersolventfreeconditions
AT maryamhasani h2so4silicacatalyzedonepotandefficientsynthesisofdihydropyrimidinonesundersolventfreeconditions
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