Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

<p>Abstract</p> <p>Background</p> <p>Activation of the extrinsic apoptosis pathway by tumour necrosis factor related apoptosis inducing ligand (TRAIL) is a novel therapeutic strategy for treating cancer that is currently under clinical evaluation. Identification of mole...

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Bibliographic Details
Main Authors:	Longley Daniel B, Paul Ian, Liberante Fabio, Chacko Alex D, Fennell Dean A
Format:	Article
Language:	English
Published:	BMC 2010-07-01
Series:	BMC Cancer
Online Access:	http://www.biomedcentral.com/1471-2407/10/380

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