The Lectin Pathway of Complement in Myocardial Ischemia/Reperfusion Injury—Review of Its Significance and the Potential Impact of Therapeutic Interference by C1 Esterase Inhibitor

The Lectin Pathway of Complement in Myocardial Ischemia/Reperfusion Injury—Review of Its Significance and the Potential Impact of Therapeutic Interference by C1 Esterase Inhibitor

Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality in modern medicine. Early reperfusion accomplished by primary percutaneous coronary intervention is pivotal for reducing myocardial damage in ST elevation AMI. However, restoration of coronary blood flow may paradox...

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Bibliographic Details
Main Authors: Anneza Panagiotou, Marten Trendelenburg, Michael Osthoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
C1 esterase inhibitor
complement system
complement inhibition
ischemia/reperfusion injury
mannose-binding lectin
myocardial infarction
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01151/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01151/full

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