Tumor Cell Dormancy and Reactivation in Bone: Skeletal Biology and Therapeutic Opportunities

ABSTRACT In the advanced stages of many cancers, tumor cells disseminate from the primary site and colonize distant locations such as the skeleton. These disseminated tumor cells colonizing bone can evade treatments and survive for prolonged periods in a dormant state before becoming reactivated to...

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Bibliographic Details
Main Authors: Niall M Byrne, Matthew A Summers, Michelle M McDonald
Format: Article
Language:English
Published: Wiley 2019-03-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10125