Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y

Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y

<p>Abstract</p> <p>Background</p> <p>SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA), but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K) is unclear. To investigat...

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Bibliographic Details
Main Authors: Sakaki Yoshiyuki, Maeda Aasami, Ozawa Ritsuko, Adati Naoki, Nishida Yuichiro, Takeda Tadayuki
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/1/95

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