The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site

The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site

Both cellular environmental factors and chemical modifications critically affect the properties of nucleic acids. However, the structure and stability of DNA containing abasic sites under cell-mimicking molecular crowding conditions remain unclear. Here, we investigated the molecular crowding effect...

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Bibliographic Details
Main Authors:	Takeshi Fujimoto, Shu-ichi Nakano, Daisuke Miyoshi, Naoki Sugimoto
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	Journal of Nucleic Acids
Online Access:	http://dx.doi.org/10.4061/2011/857149

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