Chondroitin sulfate attenuates formalin-induced persistent tactile allodynia

Chondroitin sulfate attenuates formalin-induced persistent tactile allodynia

We examined the effect of chondroitin sulfate (CS), a compound used in the treatment of osteoarthritis and joint pain, on the formalin-induced tactile allodynia in mice. A repeated oral administration of CS (300 mg/kg, b.i.d.) significantly ameliorated the formalin-induced tactile allodynia from day...

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Bibliographic Details
Main Authors: Wataru Nemoto, Kotaro Yamada, Yoshiki Ogata, Osamu Nakagawasai, Katsuhito Onodera, Hidetomo Sakurai, Koichi Tan-No
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of Pharmacological Sciences
Subjects:
Chondroitin sulfate
Tactile allodynia
Spinal cord
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316300913

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http://www.sciencedirect.com/science/article/pii/S1347861316300913

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