Low Dose Astaxanthin Treatments Trigger the Hormesis of Human Astroglioma Cells by Up-Regulating the Cyclin-Dependent Kinase and Down-Regulated the Tumor Suppressor Protein P53

Low Dose Astaxanthin Treatments Trigger the Hormesis of Human Astroglioma Cells by Up-Regulating the Cyclin-Dependent Kinase and Down-Regulated the Tumor Suppressor Protein P53

Astaxanthin (AXT) is a xanthophyll carotenoid known to have potent anti-cancer effects via upregulation of the intracellular reactive oxygen species (ROS) levels, which triggers apoptosis of cancer cells. While several studies have shown that AXT has potential as an anti-cancer drug, its effects in...

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Bibliographic Details
Main Authors: Juhyun Shin, Ramesh Kumar Saini, Jae-Wook Oh
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomedicines
Subjects:
astaxanthin
glioblastoma multiforme
reactive oxygen species
superoxide dismutase
P53
apoptosis
Online Access:https://www.mdpi.com/2227-9059/8/10/434

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