Molecular Descriptors Family on Vertex Cutting: Relationships between Acelazolamide Structures and their Inhibitory Activity

Aim: To investigate the relationship between the structural information of acetazolamides and their inhibitory activity on carbonic anhydrase II. Material and Method: A sample of previously reported acetazolamides was studied. A pool of descriptors was calculated based on matrix representation and v...

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Bibliographic Details
Main Authors: Sorana D. BOLBOACĂ, Monica M. MARTA, Carmen E. STOENOIU, Lorentz JÄNTSCHI
Format: Article
Language:English
Published: Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca 2009-12-01
Series:Applied Medical Informatics
Subjects:
Online Access:http://ami.info.umfcluj.ro/Full-text/AMI_25_2009/AMI(25)_065_074.pdf