Network and co-expression analysis of airway smooth muscle cell transcriptome delineates potential gene signatures in asthma
Abstract Airway smooth muscle (ASM) is known for its role in asthma exacerbations characterized by acute bronchoconstriction and remodeling. The molecular mechanisms underlying multiple gene interactions regulating gene expression in asthma remain elusive. Herein, we explored the regulatory relation...
Main Authors: | Priyanka Banerjee, Premanand Balraj, Nilesh Sudhakar Ambhore, Sarah A. Wicher, Rodney D. Britt, Christina M. Pabelick, Y. S. Prakash, Venkatachalem Sathish |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-93845-x |
Similar Items
-
Role of Estrogen Receptors α and β in a Murine Model of Asthma: Exacerbated Airway Hyperresponsiveness and Remodeling in ERβ Knockout Mice
by: Rama Satyanarayana Raju Kalidhindi, et al.
Published: (2020-02-01) -
Cigarette Smoke and Estrogen Signaling in Human Airway Smooth Muscle
by: Venkatachalem Sathish, et al.
Published: (2015-06-01) -
Sodium-calcium exchange in intracellular calcium handling of human airway smooth muscle.
by: Venkatachalem Sathish, et al.
Published: (2011-01-01) -
Androgen Receptor-Mediated Regulation of Intracellular Calcium in Human Airway Smooth Muscle Cells
by: Rama Satyanarayana Raju Kalidhindi, et al.
Published: (2019-07-01) -
Mechanisms of Cigarette Smoke Effects on Human Airway Smooth Muscle.
by: Mark E Wylam, et al.
Published: (2015-01-01)