Identification and Validation of Stage-Associated PBMC Biomarkers in Breast Cancer Using MS-Based Proteomics

Identification and Validation of Stage-Associated PBMC Biomarkers in Breast Cancer Using MS-Based Proteomics

Background: It is well-described that the transcriptome of peripheral blood mononuclear cells (PBMCs) can be altered in the context of many malignancies to allow them avoid the effective immune response, which leads to cancer invasiveness. Here, we used an MS-based strategy to discover biomarkers in...

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Bibliographic Details
Main Authors: Raheleh Moradpoor, Ahmad Gharebaghian, Farhad Shahi, Asadollah Mousavi, Sina Salari, Mohammad Esmaeil Akbari, Soheila Ajdari, Mona Salimi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
PBMC
breast cancer
SWATH mass spectrometry
proteome
secretome
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01101/full

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