Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats
Objectives: Diabetes mellitusmanifests itself in a wide variety of complications and the symptoms of this disease are multifactorial. Previousstudies proved that this disease is directly related to hyperglycemia and hyperlipidemia. The aim of this study was to investigate the hypoglycemic and hypoli...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2012-09-01
|
| Series: | Avicenna Journal of Phytomedicine |
| Subjects: | |
| Online Access: | http://ajp.mums.ac.ir/pdf_107_5e02dab8e9c66ddfc2b03a7f60db22dc.html |
| id |
doaj-8b2c6a96b6314ba58179be0450efc847 |
|---|---|
| record_format |
Article |
| spelling |
doaj-8b2c6a96b6314ba58179be0450efc8472020-11-24T20:51:23ZengMashhad University of Medical SciencesAvicenna Journal of Phytomedicine2228-79302228-79492012-09-0124179187107Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic ratsNajme Kafash Farkhad0Farah Farokhi1Amir Tukmacki2Khosro Soltani band3Department of Biology, Faculty of Science, Urmia University, Urmia, I. R. IranDepartment of Biology, Faculty of Science, Urmia University, Urmia, I. R. IranDepartment of Artemias Rresearch, Faculty of Veterinary, Urmia University, Urmia, I. R. IranDepartment of Artemias Rresearch, Faculty of Veterinary, Urmia University, Urmia, I. R. IranObjectives: Diabetes mellitusmanifests itself in a wide variety of complications and the symptoms of this disease are multifactorial. Previousstudies proved that this disease is directly related to hyperglycemia and hyperlipidemia. The aim of this study was to investigate the hypoglycemic and hypolipidemic effects of hydroalcoholic extract of Prangos frulacea (L.)Lindlin alloxan-induced diabetic rats. Materials and Methods: Forty female Wistar rats with body weight of 200±20 g were randomly divided into five groups with eight rats per group. Diabetes was induced in rats by alloxan monohydrate at dose of 120 mg/kg body weight (BW) injected intraperitoneally. Hydro-alcoholic extract of the root and leaves with stems of P. frulacea at 100 mg/kg BW were given orally to diabetic rats daily for 4 weeks. Result: Diabetic rats (D) exhibited a significant (phttp://ajp.mums.ac.ir/pdf_107_5e02dab8e9c66ddfc2b03a7f60db22dc.htmlDiabetes mellitusHypoglycemicHypolipidemicLipid profilePrangos ferulacea (L.) Lindl |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Najme Kafash Farkhad Farah Farokhi Amir Tukmacki Khosro Soltani band |
| spellingShingle |
Najme Kafash Farkhad Farah Farokhi Amir Tukmacki Khosro Soltani band Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats Avicenna Journal of Phytomedicine Diabetes mellitus Hypoglycemic Hypolipidemic Lipid profile Prangos ferulacea (L.) Lindl |
| author_facet |
Najme Kafash Farkhad Farah Farokhi Amir Tukmacki Khosro Soltani band |
| author_sort |
Najme Kafash Farkhad |
| title |
Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats |
| title_short |
Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats |
| title_full |
Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats |
| title_fullStr |
Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats |
| title_full_unstemmed |
Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats |
| title_sort |
hydro-alcoholic extract of the root of prangos ferulacea (l.) lindl can improve serum glucose and lipids in alloxan-induced diabetic rats |
| publisher |
Mashhad University of Medical Sciences |
| series |
Avicenna Journal of Phytomedicine |
| issn |
2228-7930 2228-7949 |
| publishDate |
2012-09-01 |
| description |
Objectives: Diabetes mellitusmanifests itself in a wide variety of complications and the symptoms of this disease are multifactorial. Previousstudies proved that this disease is directly related to hyperglycemia and hyperlipidemia. The aim of this study was to investigate the hypoglycemic and hypolipidemic effects of hydroalcoholic extract of Prangos frulacea (L.)Lindlin alloxan-induced diabetic rats.
Materials and Methods: Forty female Wistar rats with body weight of 200±20 g were randomly divided into five groups with eight rats per group. Diabetes was induced in rats by alloxan monohydrate at dose of 120 mg/kg body weight (BW) injected intraperitoneally. Hydro-alcoholic extract of the root and leaves with stems of P. frulacea at 100 mg/kg BW were given orally to diabetic rats daily for 4 weeks.
Result: Diabetic rats (D) exhibited a significant (p |
| topic |
Diabetes mellitus Hypoglycemic Hypolipidemic Lipid profile Prangos ferulacea (L.) Lindl |
| url |
http://ajp.mums.ac.ir/pdf_107_5e02dab8e9c66ddfc2b03a7f60db22dc.html |
| work_keys_str_mv |
AT najmekafashfarkhad hydroalcoholicextractoftherootofprangosferulaceallindlcanimproveserumglucoseandlipidsinalloxaninduceddiabeticrats AT farahfarokhi hydroalcoholicextractoftherootofprangosferulaceallindlcanimproveserumglucoseandlipidsinalloxaninduceddiabeticrats AT amirtukmacki hydroalcoholicextractoftherootofprangosferulaceallindlcanimproveserumglucoseandlipidsinalloxaninduceddiabeticrats AT khosrosoltaniband hydroalcoholicextractoftherootofprangosferulaceallindlcanimproveserumglucoseandlipidsinalloxaninduceddiabeticrats |
| _version_ |
1716802424170086400 |