Targeting the PI3K/Akt/mTOR pathway in estrogen-receptor positive HER2 negative advanced breast cancer
Recently many therapeutic classes have emerged in advanced hormone receptor-positive breast cancer, which is the leading cause of cancer death in women. In absence of visceral crisis, treatment relies on endocrine therapy combined with cyclin dependent kinase 4 and 6 inhibitor. Many mechanisms lead...
Main Authors: | Pauline du Rusquec, Cyriac Blonz, Jean Sebastien Frenel, Mario Campone |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-07-01
|
Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/1758835920940939 |
Similar Items
-
PI3K/AKT/mTOR pathway in Angiogenesis
by: Jayashree eKarar, et al.
Published: (2011-12-01) -
PI3K/Akt/mTOR inhibitors in breast cancer
by: Joycelyn JX Lee, et al.
Published: (2015-12-01) -
Targeting PI3K/Akt/mTOR Signaling In Cancer
by: Camillo ePorta, et al.
Published: (2014-04-01) -
AKTivation of the PI3K/AKT/mTOR signaling pathway by KSHV
by: Aadra P Bhatt, et al.
Published: (2013-01-01) -
The Role of PI3K/Akt/mTOR Signaling in Gastric Carcinoma
by: Tasuku Matsuoka, et al.
Published: (2014-07-01)