Evolution of Cortical and White Matter Lesion Load in Early-Stage Multiple Sclerosis: Correlation With Neuroaxonal Damage and Clinical Changes

Evolution of Cortical and White Matter Lesion Load in Early-Stage Multiple Sclerosis: Correlation With Neuroaxonal Damage and Clinical Changes

Introduction: Changes in cortical and white matter lesion (CL, WML) load are pivotal metrics to diagnose and monitor multiple sclerosis patients. Yet, the relationship between (i) changes in CL/WML load and disease progression and between (ii) changes in CL/WML load and neurodegeneration at early MS...

Full description

Bibliographic Details
Main Authors: Ramona-Alexandra Todea, Po-Jui Lu, Mario Joao Fartaria, Guillaume Bonnier, Renaud Du Pasquier, Gunnar Krueger, Meritxell Bach Cuadra, Marios Nikos Psychogios, Ludwig Kappos, Jens Kuhle, Cristina Granziera
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neurology
Subjects:
early relapsing remitting multiple sclerosis
MRI
MP2RAGE
cortical lesions
serum neurofilamants
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00973/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00973/full

Similar Items