Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model.

INTRODUCTION:Right ventricular (RV) myocardial dysfunction is a common feature in septic shock. It can worsen outcome, but the etiology is poorly understood. Pulmonary artery hypertension (PAH) plays a part in the pathogenesis of the right heart dysfunction in sepsis but its importance is unknown. I...

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Main Authors: Soeren Erik Pischke, Siv Hestenes, Harald Thidemann Johansen, Hilde Fure, Jan Frederik Bugge, Andreas Espinoza, Helge Skulstad, Thor Edvardsen, Erik Fosse, Tom Eirik Mollnes, Per Steinar Halvorsen, Erik Waage Nielsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218624