Adjuvant radiation therapy for a subtotally resected, low‐grade hemangiopericytoma of the cerebellum

• Main Authors: Benedict Mihangel P. Crisostomo, Edilberto Joaquin V. Fragrante, Lorelei L. Chavez
• Format: Article
• Language: English
• Published: Wiley 2020-06-01
• Series: Precision Radiation Oncology
• Subjects: adjuvant; cerebellum; hemangiopericytoma; radiotherapy
• Online Access: https://doi.org/10.1002/pro6.1091

Abstract Intracranial hemangiopericytoma of the posterior fossa represents an infrequent location for a tumor. Reported herein is a case of subtotally resected, cerebellar hemangiopericytoma, diagnosed as a grade I subtype histopathologically according to the World Health Organization classification. Controversy exists regarding whether adjuvant radiation therapy is indicated in such low‐grade, partially‐excised tumors, where treatment is typically reserved for advanced histological grades. Accounting for the biological behavior and propensity for local recurrence of this tumor histology, radiation therapy is often offered. A total dose of 5400 cGy in 30 daily fractions is administered to the residual tumor and postoperative site through 3‐D conformal techniques. Treatment is delivered with 6‐MV photons using a linear accelerator, and set‐up verification is carried out using kV imaging. In the reported case, adequate tumor coverage was achieved with respect to the pertinent organs‐at‐risk. This patient's treatment course was unremarkable, and surveillance imaging at 6 months follow up showed no evidence of residual disease. Longer follow up is recommended to adequately assess local control benefit and survival outcomes for the treatment plan given.