Ethanol effects on 68Ga-radiolabelling efficacy and radiolysis in automated synthesis utilizing NaCl post-processing

Ethanol effects on 68Ga-radiolabelling efficacy and radiolysis in automated synthesis utilizing NaCl post-processing

Abstract Objective Recent studies showed that ethanol in the reaction mixture improves radiolabelling with trivalent radiometals in terms of precursor amount, reaction time, reaction temperature and radiolysis. With regard to clinical application, this effect is of practical interest in radiopharmac...

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Bibliographic Details
Main Authors: Michael Meisenheimer, Stefan Kürpig, Markus Essler, Elisabeth Eppard
Format: Article
Language:English
Published: SpringerOpen 2019-10-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Gallium-68
Radiolysis
Radiolabelling yield
Quality control
Ethanol
Module system
Online Access:http://link.springer.com/article/10.1186/s41181-019-0076-1

Internet

http://link.springer.com/article/10.1186/s41181-019-0076-1

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