Dachsous-Dependent Asymmetric Localization of Spiny-Legs Determines Planar Cell Polarity Orientation in Drosophila

Dachsous-Dependent Asymmetric Localization of Spiny-Legs Determines Planar Cell Polarity Orientation in Drosophila

In Drosophila, planar cell polarity (PCP) molecules such as Dachsous (Ds) may function as global directional cues directing the asymmetrical localization of PCP core proteins such as Frizzled (Fz). However, the relationship between Ds asymmetry and Fz localization in the eye is opposite to that in t...

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Bibliographic Details
Main Authors: Tomonori Ayukawa, Masakazu Akiyama, Jennifer L. Mummery-Widmer, Thomas Stoeger, Junko Sasaki, Juergen A. Knoblich, Haruki Senoo, Takehiko Sasaki, Masakazu Yamazaki
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471400477X

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